Immunology

18 Resources on Immunology

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Free Web Conference • Treatment of Canine Atopic Dermatitis - What's Old and What's New (Access Oct. 10-23, 2016)

Watch this Web conference to review the pathophysiology of atopic dermatitis with an emphasis on the role of cytokines and Janus kinase enzymes.This one-hour presentation includes a discussion of the mechanism of action/efficacy/safety features of antihistamines, corticosteroids, cyclosporine, oclacitinib, and allergen-specific immunotherapy as well as a discussion on the efficacy and safety of monoclonal antibody therapy with Canine Atopic Dermatitis Immunotherapeutic (CADI) and it’s target...

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Drug-Associated Blood Cell Dyscrasias

AbstractMany therapeutic drugs have been associated with hematologic adverse drug events (ADEs) in animals. Some drugs, notably chemotherapeutic agents and oxidant compounds, cause dose-dependent bone marrow suppression, while others induce idiosyncratic ADEs. Major mechanisms associated with ADEs include immune- or oxidant-mediated destruction of blood cells and toxic bone marrow injury. General classes of drugs that can cause idiosyncratic ADEs include estrogenic compounds, NSAIDs,...

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Anemia: Determining the Cause

AbstractAnemia is a common finding in small animal practice; however, the multitude of potential causes can make determining the underlying diagnosis a challenging and frustrating endeavor. With a basic understanding of red blood cell production and a systematic diagnostic approach, clinicians should be able to clearly define the cause of anemia in most cases.Anemia refers to a reduced hemoglobin concentration due to decreased red blood cell mass. This can be expressed as a packed cell volume...

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Norwegian or Crusted Sarcoptic Mange in Two Leishmanial Dogs (Case Reports)

AbstractNorwegian or crusted scabies (N/CS) is a rare skin disease with very few cases reported in the dog or the cat. Two adult, stray dogs were admitted in our clinic with a generalized, multifocal to diffuse and nonpruritic dermatitis that was characterized by severe crusting, scaling, and ulceration. In both instances, leishmaniosis and N/CS were diagnosed by immunofluorescent antibody test serology, lymph node cytology, and skin scrapings in which high numbers of Sarcoptes mites were...

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Protection Against Feline Leukemia Virus Challenge for at Least 2 Years After Vaccination With an Inactivated Feline Leukemia Virus Vaccine

Protection Against Feline Leukemia Virus Challenge for at Least 2 Years After Vaccination With an Inactivated Feline Leukemia Virus Vaccine

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What's New in Antibiotics, Antifungals, and Antivirals for Horses

WHAT’S NEW IN ANTIBIOTICS, ANTIFUNGALS, AND ANTIVIRALS FOR HORSES ANTIBIOTICS Fluoroquinolones The fluoroquinolone class of antibiotics work via inhibition of DNA gyrase (topoisomerase II), which is required for bacterial DNA replication, transcription, repair, and recombination. Resistance is mediated through chromosomal mutations in DNA gyrase (gyrA) which confers cross-resistance to other fluoroquinolones. Fluoroquinolones distribute well to the tissues and penetrate well...

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